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Characteristic
|
M1 macrophages
|
P
|
M2 macrophages
|
P
|
|---|
|
Gender:
|
|
Female
|
99.5 (54–147)
|
NS
|
101.5 (53–136)
|
NS
|
|
Male
|
96 (61–147)
|
117 (45–186)
|
|
Age, years:
|
|
< 65
|
101 (61–147)
|
NS
|
117 (45–145)
|
NS
|
|
≥ 65
|
96 (54–147)
|
112 (53–186)
|
|
Smoking status:
|
|
Smokers
|
98.5 (61–147)
|
< 0.05*
|
117 (45–186)
|
< 0.05*
|
|
Non-smokers
|
87.5 (54–147)
|
101.5 (53–122)
|
|
Histological NSCLC type:
|
|
Adenocarcinoma
|
94.5 (54–147)
|
NS
|
111 (53–144)
|
NS
|
|
Squamous cell carcinoma
|
98 (62–136)
|
118 (45–186)
|
|
Other
|
94 (61–147)
|
117 (87–121)
|
|
Stage:
|
|
IA-IB
|
95 (62–128)
|
NS
|
119 (64–186)
|
NS
|
|
IIA-IIB
|
95.5 (54–136)
|
112 (68–150)
|
|
IIIA-IIIB
|
104 (61–147)
|
117 (45–145)
|
|
pT status:
|
|
pT1a-2b
|
96 (54–147)
|
NS
|
115 (64–186)
|
NS
|
|
pT3–4
|
97.5 (61–147)
|
117 (45–137)
|
|
Lymph node status:
|
|
Negative (N0)
|
95 (54–133)
|
NS
|
116 (64–186)
|
NS
|
|
Positive (N1-N3)
|
99 (61–147)
|
115 (45–150)
|
|
Differentiation:
|
|
Poor
|
97 (54–133)
|
NS
|
118 (53–186)
|
< 0.05*
|
|
Well-moderate
|
95 (61–147)
| |
108 (45–137)
| |
|
COPD:
|
|
Present
|
103 (73–147)
|
NS
|
116 (74–186)
|
NS
|
|
Absent
|
94.5 (54–147)
| |
115 (45–145)
|
- The number of macrophages represents median (range) per ten high-power fields in tumor tissue (the sum of macrophages in tumor islets and stroma)
- NS not significant
- *P < 0.05, Mann-Whitney test
